I went to Dr. Krem for a second opinion on my leukemia. I quickly changed to him as my primary oncologist. He took time to answer all of my questions and has a great bedside manor. I know he stays busy and still volunteered his own personal time to write a paper to help me with the VA. He refused any sort of compensation. The staff at the James Brown center are great as well. I can't recommend Dr. Krem enough. He at the time of this review is in Louisville, Ky.