Dr. Marlene Rabinovitch, MD

Reduced BMPR2 expression induces GM

jourl of experimental medicine, 2014

FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmory hypertension.

jourl of clinical investigation, 2013

Combining induced pluripotent stem cell with next generation sequencing technology to gain new

Pulmory circulation, 2013

Loss of adenomatous poliposis coli

Circulation research, 2012

Neutrophil Elastase Is Produced by Pulmory Artery Smooth Muscle Cells

AMERICAN JOURL OF PATHOLOGY, 2011

Disruption of PPAR gamma

JOURL OF CLINICAL INVESTIGATION, 2011

Inhibition of Transforming Growth Factor beta Worsens Elastin Degradation

AMERICAN JOURL OF PATHOLOGY, 2011

BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt

JOURL OF CELL BIOLOGY, 2011

Tie2-mediated loss of peroxisome proliferator

AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2009

S100A4 and Bone Morphogenetic Protein

CIRCULATION RESEARCH, 2009

Bone morphogenetic protein 2 induces pulmory angiogenesis via Wnt-beta-catenin

JOURL OF CELL BIOLOGY, 2009

SM22 alpha-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac

DEVELOPMENT, 2008

An antiproliferative BMP

JOURL OF CLINICAL INVESTIGATION, 2008

Relevant issues in the pathology and pathobiology of pulmory hypertension.

Jourl of the American College of Cardiology, 2013

Chronic effects of pulmory artery stenosis on hemodymic and structural development of the lungs

AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2013

Regulatory T Cells Limit Vascular Endothelial Injury and Prevent Pulmory Hypertension

CIRCULATION RESEARCH, 2011

Inhibiting Lung Elastase Activity Ebles Lung Growth in Mechanically Ventilated Newborn Mice

AMERICAN JOURL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2011

PPAR gamma and the Pathobiology of Pulmory Arterial Hypertension

Rabinovitch, M., 2010

Prolonged mechanical ventilation with air induces apoptosis

AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2010

Cholinergic Modulation of Angiogenesis: Role of the 7 Nicotinic Acetylcholine Receptor

JOURL OF CELLULAR BIOCHEMISTRY, 2009

LC3-mediated fibronectin mR translation induces fibrosarcoma growth by increasing connective tissue

JOURL OF CELL SCIENCE, 2009

Balloon occlusion pulmory wedge angiography

CARDIOLOGY IN THE YOUNG, 2009

Insulin resistance in pulmory arterial hypertension

EUROPEAN RESPIRATORY JOURL, 2009

VEGF blockade inhibits angiogenesis and reepithelialization of endometrium

FASEB JOURL, 2008

Molecular pathogenesis of pulmory arterial hypertension

JOURL OF CLINICAL INVESTIGATION, 2008

Pulmory arterial remodeling induced by a Th2 immune response

JOURL OF EXPERIMENTAL MEDICINE, 2008

Smooth muscle protein 22 alpha

CIRCULATION RESEARCH, 2008

Reactivation of gamma HV68 induces neointimal lesions in pulmory arteries of S100A4

AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2008

Developmental expression of LC3 alpha and beta

DEVELOPMENTAL DYMICS, 2008

Mechanical ventilation uncouples synthesis and assembly of elastin and increases apoptosis

AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2008

Mechanical ventilation with 40% oxygen reduces pulmory expression of genes that regulate lung

AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2007

Point: Counterpoint: Chronic hypoxia-induced pulmory hypertension does

JOURL OF APPLIED PHYSIOLOGY, 2007

Dysregulation of pulmory elastin synthesis and assembly in preterm lambs with chronic lung disease

AMERICAN JOURL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2007

Nuclear factor-kappa B activation in neotal mouse lung protects against lipopolysaccharide

AMERICAN JOURL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2007

Pulmory arterial hypertension is linked to insulin resistance

CIRCULATION, 2007

Pathobiology of pulmory hypertension

ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE, 2007

Cellular and molecular pathobiology of pulmory hypertension conference summary

CHEST, 2005

Mts1/S100A4 stimulates human pulmory artery

CHEST, 2005

Caspases from apoptotic myocytes degrade extracellular matrix: a novel remodeling paradigm.

FASEB jourl, 2005

Gene transfer of prostaglandin synthase maintains patency of the newborn lamb arterial duct

PEDIATRIC RESEARCH, 2005

Increased fibulin-5 and elastin in S100A4/Mts1 mice with pulmory hypertension

CIRCULATION RESEARCH, 2005

Interdependent serotonin transporter and receptor pathways regulate S100A4

CIRCULATION RESEARCH, 2005

Epidermal growth factor receptor blockade mediates smooth muscle cell apoptosis

CIRCULATION, 2005

Subversion of cellular autophagosomal machinery by R viruses

PLOS BIOLOGY, 2005

Apolipoprotein D and platelet-derived growth factor

CIRCULATION RESEARCH, 2004

Elafin-overexpressing mice have improved cardiac function after myocardial infarction

AMERICAN JOURL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2004

Pulmory arterial hypertension - Future directions - Report of a tiol Heart

CIRCULATION, 2004

Cellular and molecular pathobiology of pulmory arterial hypertension

JOURL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2004

The mouse through the looking glass - A new door into the pathophysiology of pulmory hypertension

CIRCULATION RESEARCH, 2004

S100A4/Mts1 produces murine pulmory

AMERICAN JOURL OF PATHOLOGY, 2004

S100A4/Mts1 produces murine pulmory

Am J Pathol, 2004

Apolipoprotein D and PDGF-BB synergism mediates vascular smooth muscle cell migration.

Circ Res, 2004

Apolipoprotein D inhibits platelet-derived growth factor

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2003

Low molecular weight heparin

Circulation, 2003

Temporal response and localization of integrins beta 1 and beta 3

CIRCULATION, 2003

Elafin overexpressing mice have improved cardiac function after myocardial infarction.

Am J Physiol Heart Circ Physiol, 2003

Apolipoprotein D inhibits PDGF induced v

Arterioscler Thromb Vasc Biol, 2003

Dexfenfluramine protects against pulmory hypertension in rats

JOURL OF APPLIED PHYSIOLOGY, 2002

Understanding and treating vein graft atherosclerosis

CARDIOVASCULAR PATHOLOGY, 2002

Pulmory arterial hypertension in congenital heart disease.

Cardiology clinics, 2002

Novel notions on newborn lung disease

TURE MEDICINE, 2002

Enhanced ERK-1/2 activation in mice susceptible to coxsackievirus-induced myocarditis

JOURL OF CLINICAL INVESTIGATION, 2002

Fetal pulmory artery diameters and their association with lung hypoplasia and posttal outcome

AMERICAN JOURL OF OBSTETRICS AND GYNECOLOGY, 2002

Overexpression of the serine elastase inhibitor elafin protects transgenic mice from hypoxic

CIRCULATION, 2002

Linking a serotonin transporter polymorphism to vascular smooth muscle proliferation

JOURL OF CLINICAL INVESTIGATION, 2001

Pathobiology of pulmory hypertension - Extracellular matrix

CLINICS IN CHEST MEDICINE, 2001

Arterial elastase activity after balloon angioplasty and effects of elafin, an elastase inhibitor

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2001

Tumor necrosis factor

CIRCULATION RESEARCH, 2001

Conditiol and targeted overexpression of vascular chymase causes hypertension in transgenic mice

PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AM, 2001

A novel vascular smooth muscle chymase is upregulated in hypertensive rats

JOURL OF CLINICAL INVESTIGATION, 2001

Hemodymic unloading leads to regression of pulmory vascular disease in rats

O'Blenes, S. B., Fischer, S., McIntyre, B., Keshavjee, S., RABINOVITCH, 2001

Gene transfer of the serine elastase inhibitor elafin protects against vein graft degeneration.

Circulation, 2000

Isolated ductus arteriosus aneurysm in the fetus and infant: A multi-institutiol experience

JOURL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2000

Complete reversal of fatal pulmory hypertension in rats by a serine elastase inhibitor

TURE MEDICINE, 2000

Suppressed smooth muscle proliferation

JOURL OF CLINICAL INVESTIGATION, 2000

Nitric oxide reduces vascular smooth muscle cell elastase activity through cGMP

FASEB JOURL, 2000

Under new magement - A six-month progress report on Circulation Research

CIRCULATION RESEARCH, 2000

Elastase and matrix metalloproteise inhibitors induce regression

JOURL OF CLINICAL INVESTIGATION, 2000

Pathobiology of pulmory hypertension: Impact on clinical magement.

Semirs in thoracic and cardiovascular surgery. Pediatric cardiac surge, 2000

Adventitial fibroblasts - Defining a role in vessel wall remodeling

AMERICAN JOURL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2000

Circulation research Editors' yearly report: 1999-2000

Circulation research, 2000

Pulmory hypertension: Pathophysiology as a basis for clinical decision making

JOURL OF HEART AND LUNG TRANSPLANTATION, 1999

Functiol and antigenic concentrations of alpha-1

Stiskal, J. A., Ito, S., Cox, D. W., Shenn, A. T., O'Brien, K. K., Kel, 1999

Nitric oxide mediates LC-3

FASEB JOURL, 1999

EVE and beyond, retro and prospective insights

Rabinovitch, M., 1999

Survival of Mycobacterium avium

INFECTION AND IMMUNITY, 1999

Regression of hypertrophied rat pulmory arteries

CIRCULATION RESEARCH, 1999

Targeted overexpression of elafin protects mice against cardiac dysfunction

JOURL OF CLINICAL INVESTIGATION, 1999

Induction of vascular smooth muscle cell tescin

JOURL OF CELL SCIENCE, 1999

Gene transfer in utero biologically engineers a patent ductus arteriosus in lambs by arresting

TURE MEDICINE, 1999

A serine elastase inhibitor reduces inflammation and fibrosis and preserves cardiac function

TURE MEDICINE, 1998

Tissue-specific and developmental regulation of transforming growth factor-beta

PEDIATRIC RESEARCH, 1998

Microtubule involvement in translatiol regulation of fibronectin expression by light chain 3 of

CIRCULATION RESEARCH, 1998

Elastase and the pathobiology of unexplained pulmory hypertension

CHEST, 1998

AML1-like transcription factor induces serine elastase activity in ovine pulmory artery smooth

CIRCULATION RESEARCH, 1998

Mechanisms of proliferative and obliterative vascular diseases

AMERICAN JOURL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1998

Endothelial and serum factors which include apolipoprotein A1 tether elastin to smooth muscle cells

JOURL OF CELLULAR PHYSIOLOGY, 1998

Microtubule-associated protein 1 light chain 3 is a fibronectin mR

JOURL OF CLINICAL INVESTIGATION, 1997

Regulation of tescin-C

JOURL OF CELL BIOLOGY, 1997

New insights and therapeutic strategies for postcardiac transplantation corory artery disease

RABINOVITCH, M., 1997

Pulmory hypertension: Updating a mysterious disease

CARDIOVASCULAR RESEARCH, 1997

Tescin-C, proliferation and subendothelial fibronectin in progressive pulmory vascular disease

AMERICAN JOURL OF PATHOLOGY, 1997

The committed vascular smooth muscle cell: A question of 'timing' or 'response to pressure' or both

AMERICAN JOURL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 1997

Carbon monoxide formation in the ductus arteriosus in the lamb

BRITISH JOURL OF PHARMACOLOGY, 1997

Cell-extracellular matrix interactions in the ductus arteriosus and perital pulmory circulation

SEMIRS IN PERITOLOGY, 1996

Tescin-C is induced with progressive pulmory vascular disease in rats

CIRCULATION RESEARCH, 1996

Gerbode's defect associated with acute sinus node dysfunction as a complication of infective

HEART, 1996

It all begins with eve (endogenous vascular elastase)

RABINOVITCH, M., 1996

Fusion of Leishmania amazonensis par

BRAZILIAN JOURL OF MEDICAL AND BIOLOGICAL RESEARCH, 1996

Elafin, a serine elastase inhibitor

JOURL OF CLINICAL INVESTIGATION, 1996

Functiol interplay between interleukin-1 receptor

EXPERIMENTAL CELL RESEARCH, 1996

Cohabitation of Leishmania amazonensis and Coxiella burnetii

TRENDS IN MICROBIOLOGY, 1996

Exogenous leukocyte

JOURL OF CELLULAR PHYSIOLOGY, 1996

Elastase and cell matrix interactions in the pathobiology of vascular disease.

Acta paediatrica Japonica; Overseas edition, 1995

INCREASED ELASTIN-DEGRADING ACTIVITY AND NEOINTIMAL FORMATION IN PORCINE AORTIC ORGAN

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1995

Cytokine-mediated fibronectin production

RABINOVITCH, M., Molossi, S., Clausell, N., 1995

EXPERIENCE WITH REPAIR OF CONGENITAL HEART-DEFECTS USING ADJUNCTIVE ENDOVASCULAR DEVICES

Coles, J. G., Yemets, I., jm, H. K., Lukanich, J. M., Perron, J., Wils, 1995

INCREASED RESPIRATORY SYSTEM RESISTANCE AND BRONCHIAL SMOOTH

AMERICAN JOURL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1995

LYMPHOCYTE TRANSENDOTHELIAL MIGRATION TOWARD SMOOTH-MUSCLE CELLS IN INTERLEUKIN

JOURL OF CELLULAR PHYSIOLOGY, 1995

ABNORMALITIES IN INTRAMYOCARDIAL ARTERIES DETECTED IN CARDIAC TRANSPLANT BIOPSY SPECIMENS

JOURL OF THE