Dr. Stephen Joseph Galli, MD

Effector and potential immunoregulatory roles of mast cells in IgE

CURRENT OPINION IN IMMUNOLOGY, 2006

Mast cell-derived tumor necrosis factor can promote nerve fiber elongation in the skin during

AMERICAN JOURL OF PATHOLOGY, 2006

Mast cells can enhance resistance to ske and honeybee venoms

SCIENCE, 2006

Mast Cells Are Required for Full Expression of Allergen/SEB-Induced Skin Inflammation

JOURL OF INVESTIGATIVE DERMATOLOGY, 2013

Rapid desensitization induces interlization of antigen-specific IgE on mouse mast cells.

jourl of allergy and clinical immunology, 2013

PLA2G3 promotes mast cell maturation and function.

ture immunology, 2013

Mast cell aphylatoxin receptor expression can enhance IgE-dependent skin inflammation in mice

JOURL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2013

Evidence that mast cells are not required for healing of splinted cutaneous excisiol wounds

PloS one, 2013

New models for alyzing mast cell functions in vivo

TRENDS IN IMMUNOLOGY, 2012

Evidence questioning cromolyn's effectiveness and selectivity as a 'mast cell stabilizer' in mice

LABORATORY INVESTIGATION, 2012

The Chymase Mouse Mast Cell Protease 4 Degrades TNF, Limits Inflammation

AMERICAN JOURL OF PATHOLOGY, 2012

Critical role of P1-Runx1 in mouse basophil development

BLOOD, 2012

Modulation of mTOR Effector Phosphoproteins in Blood Basophils from Allergic Patients

JOURL OF CLINICAL IMMUNOLOGY, 2012

IgE and mast cells in allergic disease

TURE MEDICINE, 2012

Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1(fl/fl) mice

BLOOD, 2011

Phenotypic and functiol plasticity of cells of inte immunity

TURE IMMUNOLOGY, 2011

Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom

JOURL OF CLINICAL INVESTIGATION, 2011

Identification of an IFN-gamma/mast cell axis in a mouse model of chronic asthma

JOURL OF CLINICAL INVESTIGATION, 2011

Basophil CD203c Levels Are Increased at Baseline

INTERTIOL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 2011

MAST CELLS AND IMMUNOREGULATION/IMMUNOMODULATION

MAST CELL BIOLOGY: CONTEMPORARY AND EMERGING TOPICS, 2011

Antiinflammatory and immunosuppressive functions of mast cells.

Methods in molecular biology (Clifton, N.J.), 2011

Thymic Stromal Lymphopoietin Contributes to Myeloid Hyperplasia and Increased Immunoglobulins

AMERICAN JOURL OF PATHOLOGY, 2010

Mast cells in allergy and infection

EUROPEAN JOURL OF IMMUNOLOGY, 2010

Regulation of secretory granule size by the precise generation and fusion of unit granules

JOURL OF CELLULAR AND MOLECULAR MEDICINE, 2010

Distinguishing Mast Cell and Granulocyte Differentiation at the Single-Cell Level

CELL STEM CELL, 2010

The role of recipient mast cells in acute and chronic cardiac allograft rejection in C57BL

JOURL OF HEART AND LUNG TRANSPLANTATION, 2010

Evidence that vitamin D-3 promotes mast cell

JOURL OF EXPERIMENTAL MEDICINE, 2010

Mast Cell-Derived TNF Can Exacerbate Mortality during Severe Bacterial Infections in C57BL

AMERICAN JOURL OF PATHOLOGY, 2010

Aphylaxis: mechanisms of mast cell activation.

Chemical immunology and allergy, 2010

Pillars article: fate of bone marrow

Jourl of immunology, 2009

Rabaptin-5 regulates receptor expression and functiol activation in mast cells

BLOOD, 2008

New developments in mast cell biology

TURE IMMUNOLOGY, 2008

IL-3 is required for increases in blood basophils in nematode infection in mice

LABORATORY INVESTIGATION, 2008

Mast cell-expressed orphan receptor CCRL2 binds chemerin

JOURL OF EXPERIMENTAL MEDICINE, 2008

The development of allergic inflammation

TURE, 2008

Immunomodulatory mast cells: negative, as well as positive, regulators of immunity

TURE REVIEWS IMMUNOLOGY, 2008

Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis

TURE MEDICINE, 2008

Basophils are back!

IMMUNITY, 2008

Mast cells: Versatile regulators of inflammation, tissue remodeling, host defense and homeostasis

JOURL OF DERMATOLOGICAL SCIENCE, 2008

IL-33 induces IL-13 production by mouse mast cells independently of IgE-Fc epsilon RI sigls

JOURL OF LEUKOCYTE BIOLOGY, 2007

TIM-1 and TIM-3 enhancement of Th2 cytokine poduction by mast cells

BLOOD, 2007

IL-33 can promote survival, adhesion and cytokine production in human mast cells

LABORATORY INVESTIGATION, 2007

Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis

TURE IMMUNOLOGY, 2007

Mast cell-derived TNF contributes to airway hyperreactivity, inflammation

JOURL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007

Roles of RabGEF1/Rabex-5 domains in regulating Fc epsilon RI surface expression and Fc epsilon RI

BLOOD, 2007

Mast cells in the promotion and limitation of chronic inflammation

IMMUNOLOGICAL REVIEWS, 2007

Mast cell-derived TNF can promote Th17 cell

BLOOD, 2007

TNF can contribute to multiple features of ovalbumin

JOURL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007

Mast cells can promote the development of multiple features of chronic asthma in mice

JOURL OF CLINICAL INVESTIGATION, 2006

Mast cell-associated TNF promotes dendritic cell migration

JOURL OF IMMUNOLOGY, 2006

RabGEF1 regulates stem cell factor

PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AM, 2006

Mast cells enhance T cell activation

JOURL OF IMMUNOLOGY, 2006

Second symposium on the definition and magement of aphylaxis

Sampson, H. A., Muñoz-Furlong, A., Campbell, R. L., Adkinson, N. F., B

A key regulatory role for histamine in experimental autoimmune encephalomyelitis

JOURL OF IMMUNOLOGY, 2006

Monomeric IgE enhances human mast cell chemokine production

JOURL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2005

Activity of the tyrosine kise inhibitor PKC412

BLOOD, 2005

Mast cell-deficient W-sash c-kit mutant Kit(W-sh

AMERICAN JOURL OF PATHOLOGY, 2005

Identification of mast cell progenitors in adult mice

PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AM, 2005

Mast cells enhance T cell activation: Importance of mast cell-derived TNF

PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AM, 2005

Pathogenesis and magement of aphylaxis: Current status and future challenges

JOURL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2005

Decreased susceptibility of mast cell-deficient Kit(W)

LABORATORY INVESTIGATION, 2005

Symposium on the definition and magement of aphylaxis: Summary report

JOURL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2005

Mast cells in the development of adaptive immune responses

TURE IMMUNOLOGY, 2005

Mast cells as tuble effector and immunoregulatory cells: Recent advances

ANNUAL REVIEW OF IMMUNOLOGY, 2005

RabGEF1, a negative regulator of Ras siglling, mast cell activation and skin inflammation.

Novartis Foundation symposium, 2005

Mast cells promote homeostasis by limiting endothelin-1-induced toxicity

TURE, 2004

RabGEF1 is a negative regulator of mast cell activation and skin inflammation

TURE IMMUNOLOGY, 2004

Immune sensitization in the skin is enhanced by antigen-independent effects of IgE

IMMUNITY, 2004

Chair's introduction. Aphylaxis.

Novartis Foundation symposium, 2004

Evidence that IgE molecules mediate a spectrum of effects on mast cell survival

PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AM, 2003

Involvement of both 'allergic' and autoimmune' mechanisms in EAE, MS and other autoimmune diseases

TRENDS IN IMMUNOLOGY, 2003

Identification of A(3) receptor

JOURL OF IMMUNOLOGY, 2003

Severe aphylactic reactions to glutamic acid decarboxylase

BMC immunology, 2003

Multiple elements of the allergic arm of the immune response modulate autoimmune demyelition

PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AM, 2003

Regulation of mast-cell and basophil function and survival by IgE

TURE REVIEWS IMMUNOLOGY, 2002

Probing the roles of mast cells and basophils in tural and acquired immunity

Marone, G., Galli, S. J., Kitamura, Y.

Transcriptiol response of human mast cells stimulated via the Fc

BMC immunology, 2002

Gene-microarray alysis of multiple sclerosis lesions yields new targets validated in autoimmune

TURE MEDICINE, 2002

Regulation of mast cell survival by IgE

IMMUNITY, 2001

An unexpected version of horror autotoxicus: aphylactic shock to a self peptide

TURE IMMUNOLOGY, 2001

Mast cells can amplify airway reactivity

JOURL OF EXPERIMENTAL MEDICINE, 2000

In vivo immunological function of mast cells derived from embryonic stem cells

PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AM, 2000

A role for Bax in the regulation of apoptosis in mouse mast cells

JOURL OF INVESTIGATIVE DERMATOLOGY, 2000

The diverse potential effector and immunoregulatory roles of mast cells in allergic disease

JOURL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2000

Mast cells and basophils

CURRENT OPINION IN HEMATOLOGY, 2000

Mast-cell heparin demystified.

ture, 1999

IgE enhances Fc epsilon receptor I expression and IgE

JOURL OF IMMUNOLOGY, 1999

Spontaneous canine mast cell tumors express tandem duplications in the proto-oncogene c-kit

EXPERIMENTAL HEMATOLOGY, 1999

Mast cells as sentinels of inte immunity

CURRENT OPINION IN IMMUNOLOGY, 1999

The c-kit ligand, stem cell factor, can enhance inte immunity through effects on mast cells

JOURL OF EXPERIMENTAL MEDICINE, 1998

Mast cells can secrete vascular permeability factor vascular endothelial cell growth factor

JOURL OF EXPERIMENTAL MEDICINE, 1998

Involvement of Bruton's tyrosine kise in Fc epsilon RI-dependent mast cell degranulation

JOURL OF EXPERIMENTAL MEDICINE, 1998

P- and E-selectins are required for the leukocyte recruitment, but not the tissue swelling

LABORATORY INVESTIGATION, 1998

Role for interleukin-3 in mast-cell and basophil development and in immunity to parasites

TURE, 1998

Involvement of interleukin-3 in delayed-type hypersensitivity

BLOOD, 1998

Impaired mast cell-dependent tural immunity in complement C3-deficient mice

TURE, 1997

Expression of functiol TrkA receptor tyrosine kise in the HMC-1 human mast cell line

BLOOD, 1997

Complexity and redundancy in the pathogenesis of asthma

JOURL OF EXPERIMENTAL MEDICINE, 1997

The Paul Kallos Memorial Lecture. The mast cell: a versatile effector cell for a challenging world.

Intertiol archives of allergy and immunology, 1997

Differential release of mast cell interleukin-6 via c-kit

BLOOD, 1997

IgE regulates mouse basophil Fc epsilon RI expression in vivo

JOURL OF IMMUNOLOGY, 1997

Absence of Fc(epsilon)RI alpha chain results in upregulation of Fc gamma RIII

JOURL OF CLINICAL INVESTIGATION, 1997

Systemic aphylaxis in the mouse can be mediated largely through IgG

JOURL OF CLINICAL INVESTIGATION, 1997

IgE enhances mouse mast cell Fc epsilon RI expression in vitro and in vivo

JOURL OF EXPERIMENTAL MEDICINE, 1997

Earthquakes: Slow down for safety

TURE, 1996

Genetic alysis reveals cell type-specific regulation of receptor tyrosine kise c

JOURL OF EXPERIMENTAL MEDICINE, 1996

Recombint human stem cell factor

JOURL OF EXPERIMENTAL MEDICINE, 1996

Identification of a committed precursor for the mast cell lineage

SCIENCE, 1996

STEM-CELL FACTOR CONTRIBUTES TO INTESTIL MUCOSAL MAST

BLOOD, 1995

DEXAMETHASONE OR CYCLOSPORINE-A SUPPRESS MAST CELL

JOURL OF IMMUNOLOGY, 1995

PROMOTION OF MOUSE FIBROBLAST COLLAGEN GENE-EXPRESSION BY MAST-CELLS STIMULATED VIA THE FC

JOURL OF EXPERIMENTAL MEDICINE, 1994

CYTOPLASMIC GRANULE FORMATION IN MOUSE PANCREATIC ACIR-CELLS

CELL AND TISSUE RESEARCH, 1994

PIECEMEAL DEGRANULATION OF MAST-CELLS IN THE INFLAMMATORY EYELID LESIONS OF INTERLEUKIN

BLOOD, 1994

MAST-CELLS AUGMENT LESION SIZE AND PERSISTENCE DURING EXPERIMENTAL LEISHMANIA

JOURL OF IMMUNOLOGY, 1994

IDENTIFICATION OF IGE-BEARING CELLS IN THE LATE-PHASE RESPONSE TO ANTIGEN IN THE LUNG AS BASOPHILS

AMERICAN JOURL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 1994

THE KIT-LIGAND, STEM-CELL FACTOR

ADVANCES IN IMMUNOLOGY, VOL 55, 1994

EFFECTS OF INTERLEUKIN-3 WITH OR WITHOUT THE C-KIT LIGAND, STEM-CELL FACTOR

AMERICAN JOURL OF PATHOLOGY, 1994

EFFECTS OF CHRONIC TREATMENT WITH THE C-KIT LIGAND, STEM-CELL FACTOR

JOURL OF CLINICAL INVESTIGATION, 1993

MAST-CELLS CONTRIBUTE TO THE CHANGES IN HEART-RATE, BUT NOT HYPOTENSION OR DEATH

JOURL OF IMMUNOLOGY, 1993

HUMAN EOSINOPHILS CAN EXPRESS THE CYTOKINES TUMOR-NECROSIS

JOURL OF CLINICAL INVESTIGATION, 1993

DISTINCT PATTERNS OF EARLY RESPONSE GENE-EXPRESSION AND PROLIFERATION IN MOUSE MAST

EUROPEAN JOURL OF IMMUNOLOGY, 1993

CLONING AND FUNCTIOL-ALYSIS OF THE MOUSE C-KIT PROMOTER

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1993

MAST-CELL ACTIVATION ENHANCES AIRWAY RESPONSIVENESS TO METHACHOLINE IN THE MOUSE

JOURL OF CLINICAL INVESTIGATION, 1993

New concepts about the mast cell.

New England jourl of medicine, 1993

REVERSIBLE EXPANSION OF PRIMATE MAST-CELL POPULATIONS INVIVO BY STEM-CELL FACTOR

JOURL OF CLINICAL INVESTIGATION, 1993

THE HUMAN RECOMBINT C-KIT RECEPTOR LIGAND, RHSCF

JOURL OF IMMUNOLOGY, 1992

THE RAT C-KIT LIGAND, STEM-CELL FACTOR

JOURL OF EXPERIMENTAL MEDICINE