Dr. Gilbert Chu, MD

Cooperative Assembly of a Protein-D Filament for Nonhomologous End Joining

JOURL OF BIOLOGICAL CHEMISTRY, 2013

Here Comes the Sun: Recognition of UV-Damaged D

CELL, 2008

Cernunnos/XLF promotes the ligation of mismatched and noncohesive D ends

PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AM, 2007

Processing of D for nonhomologous end-joining is controlled by kise activity and XRCC4/Ligase IV

JOURL OF BIOLOGICAL CHEMISTRY, 2007

Processing of D for nonhomologous end-joining by cell-free extract

EMBO JOURL, 2005

Toxicity from radiation therapy associated with abnormal transcriptiol responses to D damage

PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AM, 2004

Significance alysis of microarrays applied to the ionizing radiation response

PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AM, 2001

Electrophoretic mobility shift assays for protein-D complexes involved in D repair.

Methods in molecular biology (Clifton, N.J.), 2012

An Information Theoretic

PLOS ONE, 2011

Crystal structure of human XLF: A twist in nonhomologous D end-joining

MOLECULAR CELL, 2007

Electrophoretic mobility shift assays to study protein binding to damaged D.

Methods in molecular biology (Clifton, N.J.), 2006

Assays for nonhomologous end joining in extracts

D REPAIR, PT A, 2006

Toxicity from radiation therapy associated with abnormal transcriptiol responses to D damage

Rieger, K. E., Hong, W. J., Tusher, V. G., Tang, J., Tibshirani, R., C, 2004

Portrait of transcriptiol responses to ultraviolet and ionizing radiation in human cells

NUCLEIC ACIDS RESEARCH, 2004

Class prediction by nearest shrunken centroids, with applications to D microarrays

STATISTICAL SCIENCE, 2003

Interaction between UV-damaged D binding activity proteins and the c-Abl tyrosine kise

JOURL OF BIOLOGICAL CHEMISTRY, 2002

Xeroderma pigmentosum complementation group E and UV-damaged D-binding protein

D REPAIR, 2002

Sypsis of D ends by D-dependent protein kise

EMBO JOURL, 2002

Diagnosis of multiple cancer types by shrunken centroids of gene expression

PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AM, 2002

Supervised learning from microarray data

COMPSTAT 2002: PROCEEDINGS IN COMPUTATIOL STATISTICS, 2002

Activation of D-dependent protein kise by single-stranded D ends

JOURL OF BIOLOGICAL CHEMISTRY, 2000

Structure of D-dependent protein kise: implications for its regulation by D

EMBO JOURL, 1999

Expression of the p48 xeroderma pigmentosum gene is p53-dependent

PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AM, 1999

The use of electrophoretic mobility shift assays to study D repair.

Methods in molecular biology (Clifton, N.J.), 1999

Failure of hairpin-ended and nicked D to activate D-dependent protein kise

MOLECULAR AND CELLULAR BIOLOGY, 1998

p48 activates a UV-damaged-D binding factor

MOLECULAR AND CELLULAR BIOLOGY, 1998

D-dependent protein kise: D binding and activation in the absence of Ku

PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AM, 1998

Double strand break repair

JOURL OF BIOLOGICAL CHEMISTRY, 1997

The end-joining reaction in V(D)J recombition.

Semirs in immunology, 1997

D-dependent protein kise is not required for accumulation of p53 or cell cycle arrest after D

CANCER RESEARCH, 1997

Ku86 defines the genetic defect and restores X-ray resistance and V

MOLECULAR AND CELLULAR BIOLOGY, 1996

Isolation of a cD encoding a UV

MUTATION RESEARCH-D REPAIR, 1996

Role of the Ku autoantigen in V(D)J recombition and double-strand break repair

MOLECULAR ALYSIS OF D REARRANGEMENTS IN THE IMMUNE SYSTEM, 1996

A NOVEL ROLE FOR D PHOTOLYASE

MOLECULAR AND CELLULAR BIOLOGY, 1994

RESTORATION OF X-RAY RESISTANCE AND V(D)J RECOMBITION IN MUTANT-CELLS BY KU CD

SCIENCE, 1994

XERODERMA-PIGMENTOSUM GROUP-E BINDING-FACTOR RECOGNIZES A BROAD-SPECTRUM OF D-DAMAGE

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 1994

INVOLVEMENT OF THE KU AUTOANTIGEN IN THE CELLULAR-RESPONSE TO D DOUBLE-STRAND BREAKS

PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AM, 1994

A D END-BINDING FACTOR INVOLVED IN DOUBLE-STRAND BREAK REPAIR AND V(D)J RECOMBITION

MOLECULAR AND CELLULAR BIOLOGY, 1994

CELLULAR-RESPONSES TO CISPLATIN - THE ROLES OF D-BINDING PROTEINS AND D-REPAIR

JOURL OF BIOLOGICAL CHEMISTRY, 1994

MASSIVE CISPLATIN OVERDOSE BY ACCIDENTAL SUBSTITUTION FOR CARBOPLATIN - TOXICITY AND MAGEMENT

CANCER, 1993

PURIFICATION AND CHARACTERIZATION OF A HUMAN PROTEIN THAT BINDS TO DAMAGED D

BIOCHEMISTRY, 1993

BAG MODEL FOR D MIGRATION DURING PULSED-FIELD ELECTROPHORESIS

PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AM, 1991

PULSED-FIELD ELECTROPHORESIS OF MEGABASE-SIZED D

MOLECULAR AND CELLULAR BIOLOGY, 1991

SEPARATION OF LARGE D BY A VARIABLE-ANGLE CONTOUR-CLAMPED HOMOGENEOUS ELECTRIC-FIELD APPARATUS

ALYTICAL BIOCHEMISTRY, 1991

CISPLATIN-RESISTANT CELLS EXPRESS INCREASED LEVELS OF A FACTOR THAT RECOGNIZES DAMAGED D

PROCEEDINGS OF THE TIOL ACADEMY OF SCIENCES OF THE UNITED STATES OF AM, 1990

XERODERMA PIGMENTOSUM GROUP-E CELLS LACK A NUCLEAR FACTOR THAT BINDS TO DAMAGED D

SCIENCE, 1988

Cooperative Assembly of a Protein-DNA Filament for Nonhomologous End Joining

JOURNAL OF BIOLOGICAL CHEMISTRY, 2013

Local false discovery rate facilitates comparison of different microarray experiments

NUCLEIC ACIDS RESEARCH, 2009

Here Comes the Sun: Recognition of UV-Damaged DNA

CELL, 2008

Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES O, 2007

Processing of DNA for nonhomologous end-joining is controlled by kinase activity and XRCC4

JOURNAL OF BIOLOGICAL CHEMISTRY, 2007

Processing of DNA for nonhomologous end-joining by cell-free extract

EMBO JOURNAL, 2005

Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES O, 2004

Significance analysis of microarrays applied to the ionizing radiation response

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES O, 2001

Electrophoretic mobility shift assays for protein-DNA complexes involved in DNA repair.

Methods in molecular biology (Clifton, N.J.), 2012

An Information Theoretic

PLOS ONE, 2011

Crystal structure of human XLF: A twist in nonhomologous DNA end-joining

MOLECULAR CELL, 2007

Electrophoretic mobility shift assays to study protein binding to damaged DNA.

Methods in molecular biology (Clifton, N.J.), 2006

Assays for nonhomologous end joining in extracts

DNA REPAIR, PT A, 2006

Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage

Rieger, K. E., Hong, W. J., Tusher, V. G., Tang, J., Tibshirani, R., C, 2004

Portrait of transcriptional responses to ultraviolet and ionizing radiation in human cells

NUCLEIC ACIDS RESEARCH, 2004

Class prediction by nearest shrunken centroids, with applications to DNA microarrays

STATISTICAL SCIENCE, 2003

Interaction between UV-damaged DNA binding activity proteins and the c-Abl tyrosine kinase

JOURNAL OF BIOLOGICAL CHEMISTRY, 2002

Xeroderma pigmentosum complementation group E and UV-damaged DNA-binding protein

DNA REPAIR, 2002

Synapsis of DNA ends by DNA-dependent protein kinase

EMBO JOURNAL, 2002

Diagnosis of multiple cancer types by shrunken centroids of gene expression

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES O, 2002

p53 binds and activates the xeroderma pigmentosum DDB2 gene in humans but not mice

MOLECULAR AND CELLULAR BIOLOGY, 2002

Supervised learning from microarray data

COMPSTAT 2002: PROCEEDINGS IN COMPUTATIONAL STATISTICS, 2002

Xeroderma pigmentosum p48 gene enhances global genomic repair and suppresses UV-induced mutagenesis

MOLECULAR CELL, 2000

Activation of DNA-dependent protein kinase by single-stranded DNA ends

JOURNAL OF BIOLOGICAL CHEMISTRY, 2000

Structure of DNA-dependent protein kinase: implications for its regulation by DNA

EMBO JOURNAL, 1999

Expression of the p48 xeroderma pigmentosum gene is p53-dependent

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES O, 1999

The use of electrophoretic mobility shift assays to study DNA repair.

Methods in molecular biology (Clifton, N.J.), 1999

Failure of hairpin-ended and nicked DNA to activate DNA-dependent protein kinase

MOLECULAR AND CELLULAR BIOLOGY, 1998

p48 activates a UV-damaged-DNA binding factor

MOLECULAR AND CELLULAR BIOLOGY, 1998

DNA-dependent protein kinase: DNA binding and activation in the absence of Ku

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES O, 1998

Double strand break repair

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997

The end-joining reaction in V(D)J recombination.

Seminars in immunology, 1997

DNA-dependent protein kinase is not required for accumulation of p53 or cell cycle arrest after DNA

CANCER RESEARCH, 1997

Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy

TRENDS IN GENETICS, 1996

Ku86 defines the genetic defect and restores X-ray resistance and V

MOLECULAR AND CELLULAR BIOLOGY, 1996

Isolation of a cDNA encoding a UV

MUTATION RESEARCH-DNA REPAIR, 1996

Role of the Ku autoantigen in V(D)J recombination and double-strand break repair

MOLECULAR ANALYSIS OF DNA REARRANGEMENTS IN THE IMMUNE SYSTEM, 1996

A NOVEL ROLE FOR DNA PHOTOLYASE

MOLECULAR AND CELLULAR BIOLOGY, 1994

RESTORATION OF X-RAY RESISTANCE AND V(D)J RECOMBINATION IN MUTANT-CELLS BY KU CDNA

SCIENCE, 1994

XERODERMA-PIGMENTOSUM GROUP-E BINDING-FACTOR RECOGNIZES A BROAD-SPECTRUM OF DNA-DAMAGE

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 1994

INVOLVEMENT OF THE KU AUTOANTIGEN IN THE CELLULAR-RESPONSE TO DNA DOUBLE-STRAND BREAKS

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES O, 1994

A DNA END-BINDING FACTOR INVOLVED IN DOUBLE-STRAND BREAK REPAIR AND V(D)J RECOMBINATION

MOLECULAR AND CELLULAR BIOLOGY, 1994

CELLULAR-RESPONSES TO CISPLATIN - THE ROLES OF DNA-BINDING PROTEINS AND DNA-REPAIR

JOURNAL OF BIOLOGICAL CHEMISTRY, 1994

MASSIVE CISPLATIN OVERDOSE BY ACCIDENTAL SUBSTITUTION FOR CARBOPLATIN - TOXICITY AND MANAGEMENT

CANCER, 1993

PURIFICATION AND CHARACTERIZATION OF A HUMAN PROTEIN THAT BINDS TO DAMAGED DNA

BIOCHEMISTRY, 1993

BAG MODEL FOR DNA MIGRATION DURING PULSED-FIELD ELECTROPHORESIS

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES O, 1991

PULSED-FIELD ELECTROPHORESIS OF MEGABASE-SIZED DNA

MOLECULAR AND CELLULAR BIOLOGY, 1991

SEPARATION OF LARGE DNA BY A VARIABLE-ANGLE CONTOUR-CLAMPED HOMOGENEOUS ELECTRIC-FIELD APPARATUS

ANALYTICAL BIOCHEMISTRY, 1991

CISPLATIN-RESISTANT CELLS EXPRESS INCREASED LEVELS OF A FACTOR THAT RECOGNIZES DAMAGED DNA

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES O, 1990

XERODERMA PIGMENTOSUM GROUP-E CELLS LACK A NUCLEAR FACTOR THAT BINDS TO DAMAGED DNA

SCIENCE, 1988